Click on a column in the table below to draw on a plot here.

up-arrow: ascending order; down-arrow: descending order
CoVIC ID Isotype Epitope class KD (M) Pseudovirus neutralization (µg/mL) Authentic virus neutralization (µg/mL) In vivo protection Fc Activity (qualitative) ACE2 response (% blocking) Escape Structure Details
Full-length ectodomain D614 Full-length ectodomain D614G RBD NTD IC50 best ordering: ascending IC80 best ordering: ascending IC90 best ordering: ascending IC50 best ordering: ascending IC80 best ordering: ascending IC90 best ordering: ascending % Survival (mice) % Survival (hamsters) Phagocytosis Complement Deposition NK activation FcR binding
1 IgG1 1.83e+00 6.37e+00 1.41e+01 69.64
2 IgG1 1.71e-10 7.60e-11 1.23e-07 1.47e+00 4.01e+00 7.91e+00 100.00
3 IgG1 8.93e-07 2.32e+00 8.36e+00 1.60e+01 90.31
4 IgG1 3.34e-10 1.19e-10 1.11e-07 7.09e-01 2.48e+00 5.02e+00 100.00
5 IgG1 3.98e-07 8.53e-01 2.60e+00 5.26e+00 98.20
6 IgG1 3.06e-10 1.23e-10 1.05e-08 7.80e-02 1.91e-01 3.29e-01 100.00
7 IgG1 1.16e-09 1.49e-09 3.92e-08 3.74e+01 9.09e+01 1.51e+02 93.93
8 IgG1 9.31e-10 6.64e-10 2.36e-08 1.28e+01 2.60e+01 4.09e+01 97.95
9 IgG1 2.28e-11 1.04e-11 2.33e-10 9.29e-08 1.30e-02 2.40e-02 3.40e-02 100.00
10 IgG1 2.53e-11 1.22e-11 2.04e-10 8.55e-08 1.00e-02 2.10e-02 3.30e-02 100.00
11 IgG1 3.25e-11 1.45e-11 2.11e-10 4.67e-08 6.00e-03 1.60e-02 2.80e-02 99.45
12 IgG1 1.53e-11 7.46e-12 1.64e-10 7.55e-08 7.00e-03 1.90e-02 3.10e-02 100.00
13 IgG1 1.23e-11 6.94e-12 1.16e-10 5.11e-08 6.00e-03 1.50e-02 2.50e-02 100.00
14 IgG1 6.11e-11 1.62e-11 1.94e-09 1.00e-02 2.50e-02 4.30e-02 100.00
15 IgG1 1.30e-10 6.74e-11 1.19e-08 1.19e-07 3.20e-02 1.07e-01 2.23e-01 100.00
16 IgG1 2.16e-10 7.42e-11 5.31e-09 1.03e-06 4.50e-02 1.80e-01 3.88e-01 100.00
17 IgG1 6.94e-10 3.46e-08 1.03e+00 3.02e+00 5.63e+00 66.97
18 IgG
19 IgG 1.45e-09 1.68e-09 2.64e-08 23.66
20 IgG1 1.20e-09 8.15e-08 7.20e-02 5.87e-01 8.96
21 IgG1 6.93e-10 2.06e-09 2.08e-10 1.25e+01 4.66e+01 1.00e+02 11.58
22 IgG1 1.49e-09 4.41e-09 1.04e-07 1.28e+02 3.79e+02 6.48e+02 51.13
23 IgG1 5.14e-10 8.61e-10 7.13e-08 1.42e+01 5.21e+01 1.05e+02 36.30
24 IgG1 1.66e-09 3.39e-09 1.46e-08 1.42e+02 48.67
25 IgG1 1.48e-09 2.79e-09 8.49e-08 3.24e+02 6.87e+02 8.29e+02 31.16
26 IgG1 9.07e-10 1.74e-09 3.88e-08 31.83
27 IgG1 4.95e-09 2.09e-09 1.48e-07 8.25e+00 3.52e+01 7.11e+01 88.62
28 IgG1 4.56e-10 7.68e-10 1.23e-08 5.12e-01 1.96e+00 3.96e+00 100.00
29 IgG1 3.99e-07
30 IgG1 4.43e-11 8.75e-12 4.10e-09 2.73e-06 9.00e-03 2.70e-02 5.10e-02 100.00
31 IgG1 1.96e-10 1.19e-10 7.02e-08 1.14e+01 8.03e+01 2.33e+02 99.04
32 IgG1 7.94e-11 2.72e-11 1.76e-09 9.00e-03 3.20e-02 6.60e-02 100.00
33 IgG1 4.59e-08 2.40e-08 7.94e+01 5.81e+02 9.33e+02 7.62
34 IgG1 3.26e-09 2.57e-09 1.62e-01 4.53e-01 1.05e+00 6.38
35 IgG1 2.32e-09 1.54e-09 2.81e-09 2.59e+02 4.54e+02 6.62e+02 7.07
36 IgG1 6.01e-09 7.29e-09 9.51e-07 1.30e-01 8.50e+00 4.36e+01
37 IgG1 2.62e-08 5.82e-08 2.84e+03 3.88
38 IgG 1.50e-09 6.70e-10 7.05e-09 2.97e-01 1.31e+00 2.90e+00 99.27
39 IgG 4.30e-11 1.57e-11 1.78e-09 1.66e-06 7.00e-03 2.00e-02 3.60e-02 100.00
40 IgG 9.87e-11 5.63e-11 1.68e-08 2.48e-01 8.25e-01 1.59e+00 100.00
41 IgG1 3.21e-10 3.67e-10 2.75e-08 6.45e+00 2.32e+01 4.79e+01
42 IgG1 6.67e-10 2.35e-10 1.10e-08 5.80e-02 1.85e-01 3.48e-01 98.80
43 IgG4 2.67e-10 1.41e-10 2.27e-08 3.40e-02 1.09e-01 2.10e-01 100.00
44 IgG1 1.96e-10 2.91e-10 4.74e-08 100.00
45 IgG4 2.34e-10 5.30e-11 3.67e-08 100.00
46 IgG1 6.52
47 IgG4 3.77e-09 4.68e-09 4.61e+00 1.09e+01 1.89e+01 24.41
48 IgG1 5.72e-10 2.16e-10 1.22e-07 100.00
49 IgG4 4.55e-10 1.94e-10 1.48e-07 5.70e-02 2.19e-01 5.06e-01 100.00
50 IgG1 6.25e-10 2.50e-10 7.87e-08 8.69e-01 3.11e+00 6.47e+00 100.00
51 IgG1 13.54
52 IgG1 3.29e-10 2.23e-10 1.71e-09 2.21e-01 6.06e-01 1.08e+00 94.95
53 IgG1 1.89e-01 8.01e-01 1.73e+00 70.00
54 1.15e-09 3.48e-09 2.44e-07 3.70e-02 8.70e-02 1.39e-01 99.48
55 IgG1 2.07e-10 8.26e-11 1.15e-07 1.30e-02 3.80e-02 7.10e-02 100.00
56 IgG1 1.50e-10 5.44e-11 9.42e-08 6.00e-03 2.40e-02 5.20e-02 100.00
57 1.81e-09 3.25e-09 2.04e-07 1.00e-02 2.60e-02 4.50e-02 92.66
58 IgG1
59 6.35e-10 1.70e-09 2.01e-07 4.00e-03 1.20e-02 2.30e-02 99.40
60
61 8.25e-10 1.85e-09 1.95e-07 5.00e-03 1.60e-02 3.10e-02 99.46
62 IgG1 2.71e-10 6.80e-11 6.38e-08 8.00e-03 3.50e-02 7.40e-02 100.00
63 6.03e-10 1.52e-09 1.85e-07 3.00e-03 1.10e-02 2.30e-02 99.84
64 9.44e-10 1.85e-09 1.69e-07 1.20e-02 2.50e-02 3.90e-02 96.60
65 IgG1 1.35e-10 5.71e-11 5.10e-08 1.10e-02 2.90e-02 5.10e-02 100.00
66 7.85e-10 1.63e-09 1.40e-07 4.00e-03 1.10e-02 2.00e-02 100.00
67 IgG1 1.86e-09 8.74e-10 2.85e-07 1.75e+01 4.24e+01 7.26e+01 100.00
68 IgG1 5.72e-11 5.14e-11 2.89e-09 7.36e-03 1.64e-02 2.70e-02 100.00
69 IgG1 1.82e-09 3.14e-10 2.67e-08 6.84e+00 2.02e+01 3.54e+01 74.07
70 3.50e-09 5.40e-09 1.30e-07 6.06e-01 3.82e+00 9.90e+00 86.89
71 3.35e-09 1.81e-09 1.29e-07 8.76e-01 5.81e+00 1.82e+01 90.07
72 3.73e-09 5.31e-09 3.14e-08 1.37e-01 5.36e-01 1.11e+00 98.77
73 3.80e-09 6.48e-09 2.49e-08 3.02e-01 1.46e+00 3.27e+00 100.00
74 IgG1 7.36e-10 3.89e-10 3.42e-08 7.82e-02 2.60e+00 9.56e+00 96.23
75 IgG1 3.32e-09 1.69e-09 1.27e-07 9.65e+00 3.52e+01 7.60e+02 91.31
76 IgG1 4.84e-09 2.07e-09 1.77e-07 1.76e+01 1.10e+02 5.02e+02 92.58
77 IgG1 5.80e-09 2.55e-09 3.86e-07 2.46e+01 78.33
78 IgG1 9.57e-10 2.66e-10 3.93e-07 48.69
79 IgG1 1.17e-10 8.85e-11 7.45e-10 1.09e-01 1.50e-01 1.92e-01 99.14
80 IgG1 2.91e-09 1.73e-09 1.04e-07 7.92e-01 3.34e+00 7.60e+00 93.73
81 IgG1 1.96e-09 1.20e-09 9.88e-08 8.24e-01 4.14e+00 9.95e+00 86.84
82 IgG1 1.72e-09 2.71e-09 3.61e-08 8.65e+01 33.07
83 4.97e-10 3.04e-10 8.94e-08 1.03e+00 3.20e+00 6.03e+00 98.04
84 5.76e-10 3.96e-10 9.29e-08 1.57e+00 4.38e+00 7.70e+00 96.17
85 IgG1 3.46e-09 1.14e-09 1.51e-07 93.19
86 IgG1 2.89e-09 6.28e-10 1.03e-07 6.15e+00 2.72e+01 5.84e+01 96.80
87 IgG4 8.23
88 IgG1
89 IgG1 1.62e-09 8.03e-10 6.73e-08 5.36e-01 2.13e+00 4.47e+00 60.90
90 IgG1 3.91e-10 1.81e-10 1.10e-07 3.80e-01 1.19e+00 2.11e+00 100.00
91 IgG1 3.24e-10 8.11e-10 4.69e-09 3.27e-01 1.66e+00 4.94e+00 21.68
92 IgG1 1.38e-09 8.15e-10 1.96e-07 1.70e-01 3.95e-01 91.16
93 IgG2 1.36e-10 3.85e-11 4.31e-10 95.42
94 IgG1 1.39e-10 1.57e-10 5.62e-09 1.74e-01 2.15e-01 2.53e-01 97.97
95 IgG1 1.12e-10 6.95e-11 2.75e-08 98.84
96 IgG1 1.02e-10 8.06e-11 9.22e-08 44.82
97 IgG1 1.74e-11 8.97e-12 4.96e-09 3.41e-06 100.00
98 IgG1 9.78e-11 9.27e-11 3.82e-09 2.26e-01 4.31e-01 98.47
99 IgG1 5.36e-11 3.03e-11 2.47e-09 100.00
102 84.30
103 84.95
104 86.10
105 IgG1 2.87e-11 1.79e-11 1.62e-08 100.00
106 IgG1 1.73e-11 9.42e-12 9.24e-10 2.79e-07 100.00
107 IgG1 2.98e-11 1.43e-11 9.39e-10 2.26e-07 100.00
108 IgG1 3.04e-11 1.56e-11 1.04e-09 3.60e-07 100.00
109 IgG1 2.18e-11 1.51e-11 5.80e-10 1.96e-07 100.00
110 IgG1 3.01e-11 1.01e-11 1.53e-09 7.53e-07 100.00
111 IgG1 2.70e-11 1.44e-11 1.39e-09 3.84e-07 100.00
112 IgG1 2.37e-11 1.30e-11 3.46e-10 1.23e-07 100.00
113 IgG1 4.96e-10 3.56e-10 1.37e-09 27.19
114 IgG1 4.71e-10 3.16e-10 6.20e-10 7.49e-08 31.07
115 IgG1 5.07e-10 3.47e-10 8.54e-10 34.53
116 IgG1 1.21e-10 7.71e-11 1.03e-08 29.20
117 IgG1 1.72e-11 9.08e-12 9.06e-10 2.88e-07 64.64
118 IgG1 100.00
119
120
121
122
123
124
125
126
127 IgG1
128 IgG1
129
130
131 IgG
132 IgG
133 IgG
134 IgG
135 IgG
136 IgG
137 IgG
138 IgG
139 IgG
140 IgG
141 IgG
142 IgG
143 IgG
144 IgG1
145 IgG1
146 IgG1
147 IgG1
148 IgG1
149 IgG1
150 IgG1
151 IgG1
152 IgG1
153 IgG1
154 IgG1
155 IgG1
156 IgG1
157 IgG1
158 IgG1
159 IgG1
160 IgG1
161 IgG1
162 IgG1
163 IgG1
164 IgG1
165 IgG1
166 IgG1
167 IgG1
168 IgG1
169 IgG1
170 IgG1
171 IgG1
172 IgG1
173 IgG1
174 IgG
175 IgG
176 IgG
177 IgG
178 IgG
179 IgG
180 IgG
181 IgG1
182 IgG1
183 IgG
184 IgG
185 IgG
186 IgG
187 IgG
188 IgG
189 IgG
190 IgG
191 IgG
192 IgG
193 IgG
194 IgG
195 IgG
196 IgG
197 IgG
198 IgG
199 IgG
200 IgG
201 IgG
202 IgG1
203 IgG1
204 IgG1
205 IgG1
206 IgG1
207 IgG1
208 IgG1
209 IgG1
210 IgG